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Vaccinations Inevitably Cause Autoimmune Diseases: PLoS Study

July 26, 2012 by admin in Vaccines with 50 Comments

Autoimmune diseases are a modern plague, causing untold suffering and early, painful death. This study clearly documents that vaccinations are a primary cause.

Hypodermic with Poison Injection Bottleby Heidi Stevenson

A major curse of modern living is the advent of mass suffering from chronic autoimmune diseases. They have become the way we live and the way we die. Now, a study published in PLoS One has documented that vaccinations may be causing this plague.

The study, Self-Organized Criticality Theory of Autoimmunity, produced a wide variety of tests on animals to examine the fact that, as they stated:

Repeated immunization with antigen causes systemic autoimmunity in mice otherwise not prone to spontaneous autoimmune diseases.

They concluded:

Systemic autoimmunity appears to be the inevitable consequence of over-stimulating the host’s immune ‘system’ by repeated immunization with antigen, to the levels that surpass system’s self-organized criticality.

In other words, they found that, not only is vaccination a possible or even probable cause of autoimmune disorders, but that:

Chronic diseases are the inevitable result of vaccinations!

In their introduction, the authors further describe their discovery:

The method we have chosen was to stimulate the system maximally by antigen to the levels far beyond its steady-state just like testing the capability of automobile. In a perfectly reproducible experiments in which the mice not prone to autoimmune diseases were immunized repeatedly with antigen, we have unexpectedly and surprisingly discovered that overstimulation of immune system beyond its self-organized criticality inevitably leads to systemic autoimmunity. [Emphasis mine.]

The mice used in this experiment were ones bred to have no autoimmune disorders, so the ability to stress them to the point of inevitably suffering from autoimmune disorders is particularly significant.

Study Findings

T-cells, commonly called killer cells, are a type of lymphocyte (white blood cell). They are a critical part of the immune system. CD4+ cells are a type of T-cell. They initiate the body’s response to infections. The study found that overstimulation of CD4cells results in the induction of autoantibodies, that is, antibodies that attack the self instead of invaders. That is virtually the definition of an autoimmune disease.

The authors specifically found tissue injury like that of the disease lupus erythematosus and other autoimmune disorders.

The researchers used Staphylococcus entertoxin B (SEB) to inject mice bred for their lack of autoimmunity. Injection initially resulted in loss of energy in a particular kind of CD4+ cell, Vβ8+. These cells recovered through 7 cycles of injections. However, the Vβ8+ cells were unable to recover after the 8th injection. At that point, they started to produce the autoantibodies.

They found the following autoantibodies:

  • IgG-rheumatoid factor (RF)
  • IgM-RF
  • Anti-Sm antibody
  • RF reactive against galactose-deficient IgG

As the term rheumatoid factor seems to imply, these are significant in rheumatoid arthritis, an autoimmune disorder. The last item, anti-galactose deficiency IgG antibodies, is used as a marker to diagnose the disease.

The researchers also showed that ovalbumin (OVA) and keyhole limpet hemocyanin, also induce autoimmunity after the 8th injection. 

Autoimmune Tissue Damage

EosinophilsThe authors included graphic images of autoimmune tissue damage from the experiments.

The image on the right is of eosinophils, a type of white blood cell, in the kidneys of mice immunized 12 times. Both images are at 400X. The image on the left is (PBS) refers to a nonantigen injected. It shows grossly enlarged eosinophils resulting from autoimmune damage.

Immune complexes (ICs) of proteinuria are indications of autoantibodies. The image to the left shows the development of ICs of Immunoglobulin G (IgG), C3 (indicative of lupus erythematosus), and OVA in mice injected 12 times. As in the previous image, PBS refers to the results of the injection of a nonantigen, and the results on the bottom are injection of the known antigen, OVA. The image is of a microscopic magnification of 400X.

CD8 and anti-interferonThe next image on the right shows infiltration of CD8 cells in the kidneys and anti-interferon (IFN) autoantibodies in mice injected 12 times. The image is of a microscopic magnification of 300X. As in the prior images, PBS refers to injection of a nonantigen and OVA is the injected antigen.

Types of Damage Found

The authors state that they found the following types of tissue damage:

  • Diffuse membranous (wire-loop) glomerulonephritis in the kidney.
  • Proliferative glomerulonephritis in the kidney.
  • Infiltration of plasma cells around hepatic bile ducts.
  • Enlarged lymphoid follicles with marked germinal center in the spleen.
  • Occasional lymphocyte infiltration into the salivary glands.
  • Lymphoid cell infiltration into the thyroid
  • Perivascular infiltration of neutrophils and macrophages into the skin dermis of the auricle.
  • Positive lupus band test.

Autoimmune Diseases Are Infectious

The authors also reported that injection of the damaged CD4+ cells into the autoimmune disease-safe mice transferred the damage to them. The implications of that are huge. It means that no one suffering from an autoimmune disorder should be allowed to donate blood, because they could also be donating their diseases.

Implications

The researchers concluded:

Systemic autoimmunity appears to be the inevitable consequence of over-stimulating the host’s immune ‘system’ by repeated immunization with antigen, to the levels that surpass system’s self-organized criticality.

Starting with the A’s, autoimmune diseases include:

  • Acute Disseminated Encephalomyelitis (ADEM)
  • Acute necrotizing hemorrhagic leukoencephalitis
  • Addison’s disease
  • Agammaglobulinemia
  • Alopecia areata
  • Amyloidosis
  • Ankylosing spondylitis
  • Anti-GBM/Anti-TBM nephritis
  • Antiphospholipid syndrome (APS)
  • Autoimmune angioedema
  • Autoimmune aplastic anemia
  • Autoimmune dysautonomia
  • Autoimmune hepatitis
  • Autoimmune hyperlipidemia
  • Autoimmune immunodeficiency
  • Autoimmune inner ear disease (AIED)
  • Autoimmune myocarditis
  • Autoimmune pancreatitis
  • Autoimmune retinopathy
  • Autoimmune thrombocytopenic purpura (ATP)
  • Autoimmune thyroid disease
  • Autoimmune urticaria
  • Axonal & neuronal neuropathies

Then comes the rest of the alphabet, including lupus erythematosus, rheumatoid arthritis, multiple sclerosis, chronic fatigue syndrome, Guillain-Barré syndrome, and frankly, too many others to list here.

Here’s a more complete list.

With this information in hand, can there be any justification for the current extreme vaccination schedule that exists in virtually all nations today? Can there be any wonder that the industrialized nations giving the greatest number of vaccinations are those with the greatest infant mortality rates?

The information exposed by this study clarifies that there can be no justification for the push to vaccinate. There is also no justification for the lack of research into the effects of the full schedule of vaccines.

With this information, the routine injection of vaccines into children or adults is clearly unjustified.

Source:

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  • Jans Louis

    Oh what a surprise! ;-)

  • http://www.facebook.com/paul.fassa Paul Fassa

    I truly admire Heidi Stevenson’s no-nonsense, uncompromising approach to the terrible realities of vaccine issues and the lies surrounding them. We usually post her complete original articles on our blog – Health Maven, Escape from the Medical Mafia Matrix – http://healthmaven.blogspot.com/

  • Erwin Alber

    Thanks for confirming what many of us already knew or at least suspected Heidi! 

    I have long ago arrived at the inevitable conclusion that vaccination is an organised criminal enterprise dressed up as disease prevention by means of junk science. The entire vaccine industry needs in my opinion to be shut down for good to ut an end to this appalling medical fraud, child abuse and crime against humankind.

  • Brooklaine

    Our 10 month old daughter died when her immune system turned on her and distroyed her brain thinking it was a virus. Our 8 year old was just diagnosed with type 1 diabetes. Both autoimmune diseases. We fear our 10 year old daughter is showing signs of MS. Also autoimmune! Our 3 year old has not and will not be vaccinated.

    • http://www.facebook.com/jessie.anne.herrera Jessie Herrera

      Wow, it’s not like looks like a CLASSIC GENETIC CONNECTION. Idiot.

    • Roselynn88

      Brooklaine, I encourage you to look up and contact Dr. Rebecca Carley. She has helped thousands of parents heal their children from autoimmune diseases caused by vaccines. You can look her up on her website reversingvaccineinduceddiseases.com along with her other website drcarley.com. She educates people on how to detoxify their bodies and make their immune systems work again and actually have a healthy, thriving body. Your children can be healed of the diseases they have, and your daughter can be protected from developing/healed from MS.

  • http://profiles.google.com/crecyarrow Celtic Longbow

    Where to from here .. those responsible should not be allowed to escape Scot free for this tragedy. It is not as though they did not know, and neither can it all be laid against Pharmageddon top echelons of the Medical societies in both the USA and the UK were heavily vested in the whole matter.

    Is it time for the pitch forks and torches ?  

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  • http://www.facebook.com/paul.fassa Paul Fassa

    Nice to see a lab study confirm several epidemiological surveys that indicate non-vaccinated children do better then vaccinate kids. Good job digging this up from na-na land Heidi. I haven’t seen this study discussed anywhere else – certainly wasn’t reviewed, written about, or aired on mainstream media

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  • http://www.facebook.com/johanna.m.bachmann Johanna M Bachmann

    Schools insist on vaccinations or they will not allow your child into school. How is a parent to deal with this situation?

    • HeidiStevenson

      That’s what they say, but in most cases, you can get an exemption. Check out Alan Philips, and attorney who specializes in the subject:
      http://www.vaccinerights.com/

    • http://www.facebook.com/chris.cole.7967 Chris Cole

      Perhaps start by learning and understanding why those who do understand the science advocate widespread vaccination in the first place.

      • brothersun

        Most pediatricians don’t know how an immune system works. As Dr Nancy Turner Banks says, doctors are not trained to think, but to do a job. In medical school, you are led down an intellectual cattle chute leading you to a predetermined paradigm that people in power have decided you must adopt. And you are not allowed to move off of that path at any point in your career lest you suffer severe censure, and that fear keeps doctors from acknowledging the harm they are doing. Sadly, this is not science, but mind-control, and millions are suffering at the hands of those MDs who are too afraid to look at the evidence as Dr Wakefield did. For the real story on Dr Wakefield watch this film: http://www.ageofautism.com/2013/02/banned-wakefield-films-from-british-tv-emerge-on-youtube-after-nearly-a-decade.html

        • Tia

          There is no law that requires Immunizations. My children are not vaccinated. I sign a clause that states due to religion or strong moral conviction I refuse vaccinations. They HAVE to allow my children to go to school. If there is an outbreak of some crazy disease that there is a vaccine for, however, my children would have to stay home. Has yet to happen though…

      • Casper

        Vaccines save millions of lives. If we stopped vaccinating children, many millions would die needlessly. Certainly, we are guilty of over-vaccinating, and for schools to require non-life-saving vaccines like the HPV vaccine is just wrong. We need to THINK and search-out more information.

        The above mentioned study injected a bacterial toxin known to cause inflammation – 8 times! Yes, that is excessive. It is no wonder the mice had issues. Thankfully, we don’t usually do more than 2 boosters for most vaccines!!!

        One thing to consider, however, is the adjuvents used in these vaccines. I would guess that the adjuvents have an impact on autoimmune conditions, and certain precautions should be taken to limit the amount of specific adjuvents that get injected into any one individual.

        And NO, you don’t need to get a flu shot every year. Get the flu and let your immune system fight it!!!

        And yes, I am a scientist.

        • / Heidi Stevenson

          Thus far, I’ve seen nothing that demonstrates any life-saving benefit of vaccines. The historical records don’t show it, and year-on-year data are not representative of the whole picture.

          Yes, the study does go to an extreme – but it also shows harm with far fewer injections of bacterial toxins in a significant number of mice, and it makes quite clear that injection is, itself, an issue. Also, the specific mice used in the experiment are resistant to autoimmune diseases, which should also be a cause for concern. Most human are not engineered in that manner.

          I agree that adjuvants are a major concern in vaccines. Gaia Health has discussed the issue many times.

          Whether any vaccines are justified, I don’t know. But I am certain that we have crossed the line into absurdity in their application, and most assuredly have applied bad science to promote them.

    • Minerva

      There are exemptions, look them up and become familiar with the laws of your state or region.

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  • http://www.facebook.com/jessie.anne.herrera Jessie Herrera

    Is PLoS that journal where people can pay the journal to publish whatever they write?

    • / Heidi Stevenson

      No.

  • brothersun

    The link to the complete list of autoimmune disease list doesn’t work because the “https://” is missing. It should be: https://www.aarda.org/research_display.php?ID=47

    • / Heidi Stevenson

      Thank you very much for taking the time to let me/us know. I have now corrected that link.

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  • http://www.facebook.com/norm.marple Norm Marple

    Those pushing vaccines , in my opinion are plainly satanic murderers, without question !

  • David Zwan

    Did any of you actually read the article?
    it is not concluded that “Chronic diseases are the inevitable result of vaccinations!” But that constant activation of the immune system by the same antigen will override the immune system fail safe against development of autoimmune disease. So the conclusion in lament terms is: don’t constantly inject the same antigens into someone. But no one advise that in the first place.
    The immune cells of the mice first became anergic (not activated for a immune response, but becoming not activated.) but stopped becoming anergic after 8 times immunization, this is 8 times, every 5 days. very different from vaccinations.
    “The authors also reported that injection of the damaged CD4+ cells into the autoimmune disease-safe mice transferred the damage to them.”
    you really don’t know what you are talking about
    First off, the components of blood for human transfusion are separated after blood collection. The full blood is not transferred to another person. Leukoreduction is done to remove white blood cells because these cells will cause a immune reaction in a person with other HLA alleles. This is almost everyone, except your twin. With the lab mice this is not the cause because they all have the same genes.
    Some autoimmune disease might indeed be transferred to blood. The transferred immune cells might attack the self antigens and could activate the host immune system, this might cause a cross reaction with a chance of development of a auto immune disease. Although this is just a thought and not proved by the article cited here.
    But that aside, the conclusion of the article is not that vaccination causes auto-immune diseases. The conclusion is that stimulation with the same antigen 8x every 5 days will activate immune cells that were first anergic. This is why adjuvants are added to vaccines. To prevent immune cells becoming anergic toward the added antigen.
    And for the rest of the people commenting like “yeah you tell them! no more vaccinations! you educate us! “Read the cited article! That one is peer reviewed, that one is checked and written by people with understanding of the subject at hand and has the full information. This little page has not.

    • / Heidi Stevenson

      You discuss human blood transfusion – but it has nothing to do with this study. The study discussed direct injection of CD4+ cells into mice, not transfusion.

      The authors concluded: “Systemic autoimmunity appears to be the inevitable consequence of over-stimulating the host’s immune ‘system’ by repeated immunization with antigen, to the levels that surpass system’s self-organized criticality.”

      That’s another way of saying that overstimulation by injection of antigens causes autoimmunity. Vaccines inject antigens into the body. Ergo, too many vaccinations, even without adjuvants, will trigger autoimmune disorders – inevitably.

      The mice were bred to be resistant to autoimmune diseases. That makes the results highly significant.

      Yes, adjuvants are added because vaccines don’t work well – or at all – without them. So what? The increased number of vaccinations given, the increased number of identical vaccinations given, and the apparent intent to give yet more, clearly poses a threat to health. One of those reasons is described in this study.

      This “little” page tells the truth reported by that study. You don’t.

      • David Zwan

        “The authors concluded: “Systemic autoimmunity appears to be the inevitable consequence of over-stimulating the host’s immune ‘system’ by repeated immunization with antigen, to the levels that surpass system’s self-organized criticality.”

        That’s another way of saying that overstimulation by injection of antigens causes’ autoimmunity. Vaccines inject antigens into the body. Ergo, too many vaccinations, even without adjuvants, will trigger autoimmune disorders -inevitably.”

        there is a difference between vaccinations (activation of the immune system) and introducing antigens eading to anergicT cells followed by breaking of that anergic state by reintroducing that same
        antigen over and over again. (as said in the article “ … can be activated through repeated exposure to the same antigen and…”) You
        say “even without adjuvants”, but it are those that make the difference. Also,not all vaccines are just antigens, some are weakened forms of the pathogens and will cause an immune response by itself (and yes, there is a small chance the mutated pathogens mutate back to the pathogenic form. That is why the once with the antigens are seen as the best option)

        And you say, “vaccinations will trigger autoimmune disorders – inevitably.” But since almost the entire western population has received vaccines, why doesn’t almost everyone has an autoimmune disorder? If it is inevitably? In my country (Holland) almost everyone gets vaccinated, but
        only 0.847% have autoimmune disorder (http://www.rightdiagnosis.com/a/ai/stats-country.htm) in america 3.31%

        So maybe not inevitably.

        “The increased number of vaccinations given, the increased number of identical vaccinations given”

        on what do you base the identical part? The adjuvants? Unless they are presented to T cells by dendritic cells there is no problem. The adjuvants probably activate the toll like receptors but are not presented as antigens as so do not cause anergic T cells. Also the adjuvants cause activation of dendritic cells so there is a very small chance of T cells becoming anergic at the site of vaccination. If you mean something else, could you explain?

        But back to the point:

        yes, overstimulation by injection of a lot of the same antigen a short period of time without immune activation during the first several injections will lead to immune activation. But it is different from a vaccination:
        different antigen every time and immune activation right from the start.

        Or are you saying that repeated immune activation by different agents causes auto immunity?
        If that is the case the big danger is not vaccine, but the pathogens encountered in our daily lives.

        The authors of the study seem to conclude something similar
        From the article:

        ” It then follows that the ability of certain antigens
        such as measles virus to cause autoimmunity may be due to their ability, in conjunction with its ability to present antigen, to overstimulate CD4+ and/or CD8+ T cells of certain hosts beyond integrity of their immune system. Living organisms are constantly exposed to a broad range of environmental antigens, as exemplified by the recent re-emergence of measles virus infection among a subpopulation of Japanese young
        adults who were not vaccinated against the virus..”

        Although they seem to conclude that lack of vaccination causes re-emergence of pathogens that can cause auto-immunity. An adaptive immune response might protect against it: When memory T cells are
        present, re-infection will cause activation of those memory cells followed by an immune response. So no re-stimulation of anergic T cells (if there are any). Off course this doesn’t have to be vaccination, just an infection that leads to an adaptive immune response.

        “You discuss human blood transfusion – but it has nothing to do with this study. The study discussed direct injection of CD4+ cells into mice, not transfusion.”

        My apologies, quoted the wrong part. What I meant to quote was “It means that no one suffering from an autoimmune disorder
        should be allowed to donate blood, because they could also be donating their diseases.” and I still hold that “.. Not proved by the article cited
        here. ” and that transferred blood doesn’t not hold immune cells.

        It is no great secret that some pathogens can cause auto immune diseases, a consequence of molecular mimicry and genetic makeup of the infected. And therefore it is logical that vaccination against such a pathogen, thus with the same antigens, has a risk of causing an auto immune disease. But I don’t see the study you cite proving that. It just proves that over stimulation with the same antigen in a short period of time will break a failsafe against autoimmunity. The method is very different from vaccination, as I have explained several times. And for vaccines to cause auto-immunity: it has to a pathogen with the ability
        to do that. If you really want a good article about vaccine and auto-immunity I recommend the following review: Vaccination and autoimmune disease: what is the evidence? David C Wraith, Michel Goldman, Paul-Henri Lambert THE LANCET •Published online June 3, 2003. It looks at several follow up studies involving vaccinations and auto immune disease. Although not one of the studies seems to prove a link between auto-immunity and vaccines.

        • / Heidi Stevenson

          You’re missing a highly significant point. We don’t naturally encounter pathogens by injection. Vaccinations ARE the issue here, because injection of antigens is what the study was about and vaccines inject antigens.

  • Jim Harbin

    I restarted a medicine that in the past gave me a slight rash the same week I got a flu vaccine. The rash blew up into my skin turning red and hot to touch followed by peeling only after 3 pills. That’s the end of vaccines for me.

  • Harold Steiner

    A little knowledge is a dangerous thing. Especially in the hands of someone with an axe to grind.

    This study is terrible. The authors do not explain their methods sufficiently in terms of the composition of their vaccinations or how long the injections take place. Is that one injection of 500ug OVA every 5 days 8 (or 12) times? Or is it 8 injections of 500ug OVA a day every 5 days? Or is it an injection of OVA concentrated 8 times every 5 days? The way the paper is written is not clear. Further, did they use an adjuvant in their injection? What kind? The authors do not address this.

    That’s not nit-picking, either. Those are significant details for assessing the conclusions the authors reach. In particular, this is because it is a well known fact that overstimulating the immune system via vaccination will induce autoimmunity. That’s how autoimmune conditions are modeled in animals. That’s why vaccination schedules are carefully tested to avoid inducing too much of a response.

    Scientists do not question the idea that overly-frequent vaccination has health implications. The issue at hand is what “overly-frequent” means. Mice are not humans; an 8 week old mouse is considered an adult, and the frequency of vaccination seen in this paper has no equivalent in man.

    If you want to say that the current vaccine schedule for children is “overly-frequent,” make that case. But given that the Institute of Medicine studied the schedule and found it to be safe, you’re going to have to start by explaining where they went wrong and what they missed.

    http://www.iom.edu/Reports/2013/The-Childhood-Immunization-Schedule-and-Safety.aspx

  • / Heidi Stevenson

    The rules of comment have been provided under the Home tab. Someone started a comment with the statement, “A little knowledge is a dangerous thing. Especially in the hands of someone with an axe to grind.” That person broke the no ad hominem attacks rule.

  • Minerva

    I got diagnosed with Hashis six months after a vaccination. Went from being able to run 8 miles to being unable to get out of bed, in the span of a few months. I have no doubt that vaccinations can trigger auto immune disease.

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  • courageandhope

    In trying to find this article on the mice again, I came across a collection of short summaries of articles from about ten years ago on allergies, asthma, and anaphylaxis. http://vran.org/health-risks/anaphylaxis-allergies-and-asthma/can-vaccines-cause-immune-dysfunction-resulting-in-allergies-asthma-and-anaphylaxis/ (from the Vaccine Risk Awareness Network). Wondering if “allergy” was a kind of “auto-immune response,” I learned they are similar but different “hypersensitivities” of the immune system. In allergy, the body attacks outside invaders, antigens, while in autoimmune disorder, the body attacks healthy tissue. MedlinePlus says with an autoimmune disorder, the body can’t tell the difference between healthy tissue and an antigen. http://www.nlm.nih.gov/medlineplus/ency/article/000816.htm

    It is interesting to me that the phenomenon of allergy was first observed in the context of immunizations. It was an immunologist, von Pirquet, who coined the term “allergy.” According to Wikipedia: “In 1906 he noticed that patients who had previously received injections of horse serum or smallpox vaccine had quicker, more severe reactions to a second injection. He, along with Bela Schick, coined the word allergy (from the Greek allos meaning “other” and ergon meaning “reaction”) to describe this hypersensitivity.”
    http://en.wikipedia.org/wiki/Clemens_von_Pirquet. (Normally I would not quote Wikipedia, but I got this from a library book I no longer have around.) Thanks for the good article, Heidi.

  • cesca_nz

    My son was diagnosed with Type 1 Diabetes at age 10.

    I have reason to believe that the group of vaccinations he got as a child (aged 18 to 20 months) were the cause or the TRIGGER for his diabetes. My son received the MMR vaccine first dose as his 7th dose of antigen at age of 12 months.

    Six months later at age 18 to 20 months, he was given a DTAP vaccination as well as 2 flu vaccinations all within 6 weeks. It was December and January and we were in the middle of a cold snowy winter. My son was having an episode of what the doctors called “bronchiolitis” at the time and spent 5 days in hospital. I think that DTAP and the 2 flu vaccinations were the trigger for his diabetes. They would have been the 8th, 9th and 10th doses of antigen.

    Of course I have no proof of this – but since science still don’t know (or claim they dont know) what the triggers for diabetes are – my personal opinion is that these vaccines were my sons triggers.

    Both myself and my father also have autoimmune diseases – so my son had the genetic susceptibility – but we do not have Type 1 diabetes.

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